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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease multiple endocrine neoplasia type 1
Comorbidity C0021670|insulinoma
Sentences 8
PubMedID- 25047095 Novel mutation 928g>c of men1 gene in a familial multiple endocrine neoplasia type 1 case (men1) with co-existence of insulinoma and glucagonoma.
PubMedID- 26527982 The median age at diagnosis is about 47 years, except in insulinoma patients with men 1, in whom the median age is the mid-20’s [4].
PubMedID- 24459236 insulinoma may be associated with the multiple endocrine neoplasia type 1 in 4-6% of patients.
PubMedID- 22785103 Clinical features of insulinoma in patients with multiple endocrine neoplasia type 1: analysis of the database of the men consortium of japan.
PubMedID- 23569534 men1 patients with insulinoma are usually admitted to the hospital for a relapse of hypoglycemia.
PubMedID- 23102680 Methods: eight 12-month-old conditional men1 knockout mice with insulinoma were assessed.
PubMedID- 20464709 insulinoma in a patient with men 1 syndrome--9-year follow-up: case report.
PubMedID- 22584725 There is general consensus to submit men1 patients with insulinoma and a hypoglycaemia syndrome to surgery after biochemical diagnosis and fasting test verification, more or less irrespective of tumor size, since no efficient medical treatment option is available (2),(11),(18),(19),(39)–(43).

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